This article argues that the most unique characteristic of the ICAN’s activism is its transnational scope, which was made possible by the use of eight strategies by the organization including geostrategic headquarters, internet and technology, government relations, NGOs connection, celebrity spotlight, perfect timing, creativity, and responsiveness. In evaluating the argument, this article provides evidence by employing process-tracing methods and conducting archival analysis to closely examine the historical timeline of important events or moments surrounding the ICAN’s activism since its inception in 2007 to the adoption of the Treaty on the Prohibition of Nuclear Weapons in 2017. This article first provides a literature review on social movements against nuclear weapons to provide some background. It then describes how the eight strategies are employed by the ICAN as they are reflected in its transnational activism. It finally notes the five key milestones that are achieved by the organization.